Chagnon Family - Brain Canada Multi-Investigator Research Initiative (MIRI) Interventions for Prevention of Alzheimer Disease and Related Disorders

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The deadline for the Chagnon Family and Brain Canada Interventions for Prevention of Alzheimer Disease and Related Disorders (ADRD) Multi Investigator Research Initiative (MIRI) was February 22, 2013 and the competition is now closed.  
A total of 23 Letters of Intent (LOI’s) were received from across Canada for consideration.
Click here to view a Summary Report.
The results of the LOI review were sent to applicants electronically the week of May 6th, 2013.  
Click here to view the list of LOIs that advanced to the full application stage
Click here to view the list of funded projects


Supported by a joint venture between the Chagnon Family and Brain Canada (Canada Brain Research Fund), the purpose of these MIRI grants is to accelerate novel and transformative intervention research that will improve the prevention of Alzheimer Disease and Related Disorders (ADRD). This will be the largest investment in interventions for prevention of ADRD ever made in this country and sets forth a challenge to fast-track a quantum leap in the field.

This initiative will rewardoutside the boxideas by supporting research that is truly innovative and may challenge standard paradigms. The Partners aim to support potentially high-gain research that might have difficulty being funded by other agencies, perhaps because it is conceptually ahead of its time, involves unusual alliances between disciplines, and features novel approaches, including interventions involving complementary and alternative medicine, and alternative uses for existing medications approved for other conditions.

Over the next five years, $25 million will be provided by the Chagnon Family and Brain Canada, through the Canada Brain Research Fund; additional funds in the subsequent five years may also be possible. It is expected that three to five teams will be funded, in the range of $1-2 million per year per team. This competition is exclusively for research dealing with interventions in human subjects, intended to lead to new prevention strategies and preventive treatments for ADRD.

There will be a two-stage application process, beginning with a letter-of-intent which will be reviewed by an expert international selection committee, after which authors of the most promising proposals will be invited to submit a full application for review. The most important selection criterion will be the potential to develop effective strategies for primary and secondary prevention of ADRD, informed by the additional criteria of: innovation and originality; feasibility; and multidisciplinarity and teamwork.

Request for Applications:  ADRD_MIRI_RFA_EN.pdf

Announcement in PDF Format: ADRD_MIRI_announcement_EN.pdf

Frequently Asked Questions: FAQs

Selection Committee Evaluation Information: Selection_Committee_Evaluation_Information.pdf

For further Information:

About Brain Canada and the Canada Brain Research Fund:

About this competition: